Routes of synthesis and biological significances of Imidazole derivatives: Review

Abstract

Imidazole is a five membered, heterocyclic ring containing two hetero (nitrogen) atoms and two double bonds. Many imidazoles molecules are synthesized either through fusion or substituting various functional groups in the lead moiety. Several methods of synthesis were reported till date. Imidazole has already been reported to possess many biological activities like anticancer, analgesic, anti-inflamatory, antiviral, antihelmintic, anticonvulsant, aniallergic, antiulcer etc. the article here focus on various synthetic procedures and biological properties chemistry and major reactions of various imidazole derivatives in a comprehensive manner.